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Lewis Drug

Medical / Pharmacies

2701 S Minnesota Ave, Ste 1,
Sioux Falls, SD 57105

(605) 367-2000

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Since 1942, shoppers have trusted family-owned Lewis as their neighborhood store and pharmacy. With 45 stores conveniently located throughout South Dakota, Iowa and Minnesota!

In addition to quality prescription and non-prescription drugs, Lewis has a huge selection of everyday basics, plus name brands and specialty items—always at affordable prices.

You’ll find everything on your list along with a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

At Lewis, we promise you’ll be greeted with exceptional prices, friendly service and great products every time you walk through our doors. Make Lewis your first stop for all your family’s needs.

Business Hours

Monday 9:00 AM - 6:00 PM

Tuesday 9:00 AM - 6:00 PM

Wednesday 9:00 AM - 6:00 PM

Thursday 9:00 AM - 6:00 PM

Friday 9:00 AM - 6:00 PM

Saturday Closed

Sunday Closed